Publications

bioRxiv preprints
  1. Breuss, M.W., Yang, X., Antaki, D., Schlachetzki, J.C.M., Lana, A.J., Xu, X., Chai, G., Stanley, V., Song, Q., Newmeyer, T.F., Nguyen, A., Cao, ., NOTT, A., McEvoy-Venneri, J., Pasillas, M.P., Nahas, S., Van Der Kraan, L., Ding, Y., NIMH Brain Somatic Mosaicism Network, Glass, C.K., Gleeson J.G.  Somatic mosaicism in the mature brain reveals clonal cellular distributions during cortical development. (2020) bioRxiv doi: https://doi.org/10.1101/2020.08.10.244814.
2021
  1. NOTT*,§, A., Schlachetzki*,§, J.C.M., Fixsen, B.R., Glass§, C.K.  Nuclei isolation protocol for omics interrogation of multiple brain cell types. (2021) Nat Protoc. doi: 10.1038/s41596-020-00472-3.   *Authors contributed equally   §Corresponding author
2020
  1. Morshed, N., Ralvenius, R.T., NOTT, A., Watson, A., Rodriguez F.H., Akay, L.A., Joughin, B.A., Pao, P.-C., Penney, J., LaRocque, L., Mastroeni, D., Tsai, L.-H., White, F.M.  Phosphoproteomics identifies microglial Siglec-F inflammatory response during neurodegeneration. (2020) Mol Syst Biol. 16:e9819   (bioRxiv preprint version: https://doi.org/10.1101/2020.05.12.090688)
  2. Pao, P.-C., Patnaik, D., Watson, L.A., Gao, F., Pan, L., Wang, J., Adaikkan, C., Penney, J., Cam, H., Huang, W.-C., Rubino, L.P., Lee, A., NOTT, A., Phan, T.X., Gjoneska, E., Elmsaouri, S., Haggarty, S.J., Tsai, L.-H.  HDAC1 modulates OGG1-initiated oxidative DNA damage repair in the aging brain and Alzheimer’s disease. (2020) Nat Commun. 11(1):2484.
2019
  1. NOTT*, A., Holtman*, I.R., Coufal*, N.G., Schlachetzki, J.C.M., Yu, M., Hu, R., Han, C.Z., Pena, M., Xiao, J., Wu, Y., Keulen, Z., Pasillas, M.P., O’Connor, C., Nickl, C.K., Schafer, S.T., Shen, Z., Rissman, R.A., Brewer, J.B., Gosselin, D., Gonda, D.D., Levy, M.L., Rosenfeld, M.G., McVicker, G., Gage, F.H., Ren, B., Glass, C.K.  Brain cell type-specific enhancer-promoter interactome maps and disease-risk association. (2019) Science 366(6469):1134-1139.   *Authors contributed equally   (bioRxiv preprint version: https://doi.org/10.1101/778183)
  2. Sakai*, M., Troutman*, T.D., Seidman*, J.S., Ouyang, Z., Spann, N.J., Abe, Y., Ego, K.M., Bruni, C.M., Deng, Z., Schlachetzki, J.C.M., NOTT, A., Bennett, H., Chang, J., Vu, B.T., Pasillas, M.P., Link, V.M., Texari, L., Heinz, S., Thompson, B.M., McDonald, J.G., Geissmann, F., Glass, C.K.  Liver-Derived Signals Sequentially Reprogram Myeloid Enhancers to Initiate and Maintain Kupffer Cell Identity. (2019) Immunity. 51(4):655-670.
2018
  1.   NOTT, A., Glass C.K. Immune memory in the brain. (2018) Nature. 556(7701):312-313.
2016
  1. NOTT§, A., Cheng, J., Gao, F., Lin, Y.-T., Gjoneska, E., Ko, T., Minhas, P., Zamudio, A.V., Meng, J., Zhang, F., Jin, P., Tsai, L.-H.  Histone deacetylase 3 associates with MeCP2 to regulate FOXO and social behavior. (2016) Nat Neurosci. 19(11):1497-1505.   §Corresponding author
  2. Seneviratne*, U., NOTT*, A., Bhat, V., Kodihalli, R., Wishnok, J., Tsai, L.-H., Tannenbaum, S.R.  S-nitrosation of proteins relevant to Alzheimer’s disease during early stages of neurodegeneration. (2016) Proc Natl Acad Sci USA. 113(15):4152-7.   *Authors contributed equally
  3. Nitarska, J., Smith, J.G., Sherlock, W.T., Hillege, M.H.H., NOTT, A., Barshop, W.D., Vashisht, A.A., Wohlschlegel, J.A., Mitter, R., Riccio, A. A functional switch of the NuRD chromatin remodeling complex subunits regulates mouse cortical development. (2016) Cell Reports. 17:1683-98.
  4. Durak, O., Gao, F., Kaeser-Woo, Y.J., Rueda, R., Martorell, A., NOTT, A., Liu, C.Y., Watson, L.A., Tsai, L.-H. The chromatin remodeler Chd8 transcriptionally regulates cell cycle and neurogenesis in the developing mouse cortex. (2016) Nat Neurosci. 19(11):1477-1488.
2015
  1. Madabhushi, R., Gao, F., Pfenning, A.R., Pan, L., Yamakawa, S., Seo, J., Rueda, R., Phan, T.X., Yamakawa, H., Pao, P.C., Stott, R.T., Gjoneska, E., NOTT, A., Cho, S., Kellis, M., Tsai, L.-H. Activity-induced DNA breaks govern the expression of neuronal early-response genes. (2015) Cell. 161(7):1592-605.
  2. NOTT*, A., Cho*, S., Seo, J., Tsai, L.-H. HDAC2 expression in parvalbumin interneurons regulates synaptic plasticity in the mouse visual cortex. (2015) Neuroepigenetics. 1(1):34-40.   *Authors contributed equally
2013
  1. NOTT, A., Nitarska, J., Veenvliet, J.V., Schacke, S., Derijck, A.A., Sirko, P., Muchardt, C., Pasterkamp, J., Smidt, M.P., Riccio, A. S-Nitrosylation of HDAC2 regulates the expression of the chromatin remodeling factor Brm during radial neuron migration. (2013) Proc Natl Acad Sci USA. 110(8):3113-8.
  2. NOTT, A., Tsai, L.-H. The Top3β way to untangle RNA. (2013) Nat. Neurosci. 16(9):1163-4.
2012
  1. NOTT, A., Fass, D.M., Haggarty, S.J., Tsai, L.-H. HDAC inhibitors as novel therapeutics in aging, and alzheimer’s disease. (2012) In: Epigenetic Regulation in the Nervous System. (Sweatt, J.D., Meaney, M., Nestler, E., Akbarian, S. ed’s) Oxford: Academic Press. Pp. 224-49.
2009
  1. NOTT, A., Riccio, A. Nitric oxide-mediated epigenetic mechanisms in developing neurons. (2009) Cell Cycle. 8:725-30.
  2. NOTT, A., Riccio, A. Regulation of Histone Deacetylases: the Role of Nitric Oxide. (2009) In: Epigenetic Control and Neuronal Function. (Sassone-Corsi, P. ed) Washington, DC: Society for Neuroscience. pp. 35-43.
2008
  1. NOTT, A., Watson, P.M., Robinson, J.D., Crepaldi, L., Riccio, A. S-nitrosylation of histone deacetylase 2 induces chromatin remodeling in neurons. (2008) Nature. 455(7211):411-5.
  2. NOTT, A., Robinson, J.D., Riccio, A. DAF-FM detection of nitric oxide in embryonic cortical neurons. (2008) Protocol Exchange | Nature Research. DOI: 10.1038/nprot.2008.235
2006
  1. NOTT, A., Levin, E.D. Dorsal hippocampal alpha7 and alpha4beta2 nicotinic receptors and memory. (2006) Brain Research. 1081(1):72-8.